Encephalopathy associated with Hashimoto's thyroiditis: an additional case

M Bertoni; M Falcini; S Sestini; L Niccoli; C Nannini; F Cantini

doi:10.1016/j.ejim.2003.06.002

Encephalopathy associated with Hashimoto's thyroiditis: an additional case

Eur J Intern Med. 2003 Nov;14(7):434-437. doi: 10.1016/j.ejim.2003.06.002.

Authors

M Bertoni¹, M Falcini, S Sestini, L Niccoli, C Nannini, F Cantini

Affiliation

¹ Divisione di Medicina Interna, Ospedale di Prato, Piazza Ospedale 1, I-59100, Prato, Italy

PMID: 14614977
DOI: 10.1016/j.ejim.2003.06.002

Abstract

A 35-year-old female with a history of Hashimoto's thyroiditis (HT) presented with episodic dysphasia and a burst of axial jerks with abdominal muscle contraction and asymmetric blepharospasm as manifestations of encephalopathy associated with HT. Brain magnetic resonance imaging (MRI) showed scattered supratentorial white matter hyperintense T2 foci. Brain single photon emission computerized tomography (SPECT) demonstrated a cortical hypoperfusion in the upper frontal and parietal areas. Corticosteroid therapy induced a rapid improvement of the clinical picture.