[Benign intracranial hypertension. History, clinical features and treatment in a series of 41 patients]

Rev Neurol. 2003 Nov;37(9):801-5.
[Article in Spanish]

Abstract

Introduction: Benign intracranial hypertension (BIH) is a syndrome characterized by the abnormal elevation of the intracranial pressure with a normal composition of the cerebrospinal fluid (CSF) and in absence of ventriculomegaly or some intracranial expansive lesion.

Aim: The present work seeks, by means of the analysis of diagnosed BIH patients to evaluate its epidemic, clinical and therapeutic features.

Patients and methods: 87 histories from intracranial hypertension diagnosed patients with normal cerebral CT were reviewed, between 1999 and 2002. 41 BIH patients were selected.

Results: The reached results allow us to draw the following profile, a woman (> 70%) of between 21 and 30 years (29%), smoker, obese (59%) with an recent increase of weight (37%) that consults after spending more than three months with headache (89%), alterations of the visual acuity (> 50%) and nauseas with some vomiting (> 40%). In the exploration, it presents with bilateral papilledema (100%), a CSF pressure bigger than 20 cmH2O (40,78 15,55 cmH2O) with normal composition, without alterations in the neuroradiological study results.

Conclusion: The treatment with acetazolamide was favourable (51,2%), being definitive (70%) the lumbar peritoneal shunt when it is specified (30,7%), being improved these figures in those patients with a smaller pressure of the CSF in the moment of the diagnosis (p<0,035).

Publication types

  • English Abstract
  • Review

MeSH terms

  • Acetazolamide / therapeutic use
  • Adolescent
  • Adult
  • Cerebrospinal Fluid Shunts
  • Child
  • Child, Preschool
  • Comorbidity
  • Female
  • Headache / etiology
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Neuroprotective Agents / therapeutic use
  • Obesity / epidemiology
  • Papilledema / etiology
  • Pseudotumor Cerebri / complications
  • Pseudotumor Cerebri / drug therapy
  • Pseudotumor Cerebri / epidemiology*
  • Pseudotumor Cerebri / surgery
  • Retrospective Studies
  • Smoking / epidemiology
  • Vision Disorders / etiology
  • Vomiting / etiology

Substances

  • Neuroprotective Agents
  • Acetazolamide