Abstract
Objective:
The purpose of this study was to establish whether addition of a 2% chlorhexidine rinse to a conventional treatment protocol enhances the rate of the successful disinfection of the root canal system in vivo.
Study design:
Twenty-four teeth with infected necrotic pulps and resorbing apical periodontitis were treated with a conventional technique in which 1% NaOCl as irrigant was used. Half of the cases received an additional rinse with 2% chlorhexidine. Prereduced thioglycollate medium was used to take cultures that were incubated for 4 weeks.
Results:
Cultivable bacteria were retrieved at the conclusion of the first visit in 1 out of 12 chlorhexidine cases whereas in the control group 7 out of 12 cases showed growth. This difference was significant (P < .05).
Conclusion:
The findings are clinically important.
Publication types
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Clinical Trial
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Randomized Controlled Trial
MeSH terms
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Adolescent
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Adult
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Aged
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Anti-Infective Agents, Local / administration & dosage
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Anti-Infective Agents, Local / therapeutic use*
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Bacteria / growth & development
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Calcium Hydroxide / therapeutic use
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Chi-Square Distribution
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Child
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Chlorhexidine / administration & dosage
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Chlorhexidine / therapeutic use*
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Dental Pulp Cavity / drug effects
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Dental Pulp Cavity / microbiology
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Dental Pulp Necrosis / therapy
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Disinfectants / administration & dosage
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Disinfectants / therapeutic use
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Drug Combinations
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Follow-Up Studies
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Humans
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Middle Aged
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Periapical Periodontitis / therapy
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Root Canal Filling Materials / therapeutic use
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Root Canal Irrigants / therapeutic use*
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Single-Blind Method
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Sodium Hypochlorite / administration & dosage
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Sodium Hypochlorite / therapeutic use
Substances
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Anti-Infective Agents, Local
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Disinfectants
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Drug Combinations
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Root Canal Filling Materials
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Root Canal Irrigants
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Sodium Hypochlorite
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Calcium Hydroxide
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Chlorhexidine