Following the CJD protocol and decontamination processes (Table 1) as recommended in the Health Canada CJD Guideline will serve to prevent transmission of CJD via surgical instruments, "Preparation of the work area" and "safe handling of strong chemicals used for decontamination" are other topics that must be addressed by staff in the OR and SPD. The appendix offers a quick reference that summarizes many of the important points which staff in the OR caring for patients, and staff in SPD caring for instruments, need to be aware of.