A descriptive analysis was performed of malignant melanoma data ascertained by the University of Miami School of Medicine/Jackson Memorial Hospital (UM/JMH) Tumor Registry. A total of 376 melanoma cases were collected and reviewed. Most of the melanoma lesions occurred on the trunk, especially in the 40- to 49- and 50- to 54-year-old age groups. Local-stage cases had the best 5-year survival--77%. The difference in survival between local-stage case and regional- and distant-stage cases was statistically significant (p = 0.0000). In males with local-stage disease, lesions on the trunk were associated with better survival than lesions at other sites (p = 0.04). In females with local-stage disease, survival was 68% for 5 years for trunk sites vs. 87% for other sites (p = 0.05). In local-stage disease, the overall 5-year survival was 85%.