The aim is to describe 5 cases of unexplained visual impairment after uneventful episcleral surgery associated with submacular lesions occurring post-operatively (bleb-like syndrome). The 5 cases were followed with biomicroscopy and OCT for up to 6 months. At biomicroscopy the 5 eyes presented no visible abnormalities or a yellow subfoveal dot. OCT demonstrated the presence of isolated or multiple subfoveal or submacular blebs. Some cases experienced partial or total slow spontaneous resolution, while other blebs remained stable for months or slightly enlarged. In conclusion, OCT can play an important role in the follow up of patients with unexplained visual impairment after episcleral surgery and diagnose the presence of small subfoveal shallow retinal detachments persistent for months after surgery. We think that OCT should be routinely considered in the follow-up of these patients.