Aryl-beta-C-LNA monomers as universal hybridization probes

B Ravindra Babu; Jesper Wengel

doi:10.1081/NCN-120022955

Aryl-beta-C-LNA monomers as universal hybridization probes

Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1317-9. doi: 10.1081/NCN-120022955.

Authors

B Ravindra Babu¹, Jesper Wengel

Affiliation

¹ Nucleic Acid Center, Department of Chemistry, University of Southern Denmark, Odense M, Denmark.

PMID: 14565408
DOI: 10.1081/NCN-120022955

Abstract

High-affinity universal hybridization is demonstrated for oligonucleotides containing the pyrenyl-LNA monomer 6b, 2'-O-Me-RNA monomers and LNA monomers.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Base Sequence
Nucleic Acid Conformation
Nucleic Acid Hybridization
Oligodeoxyribonucleotides / chemistry
Oligonucleotide Probes
Oligonucleotides
Oligonucleotides, Antisense / chemistry*

Substances

Oligodeoxyribonucleotides
Oligonucleotide Probes
Oligonucleotides
Oligonucleotides, Antisense
locked nucleic acid