Abstract
Beta-D-pentofuranonucleoside derivatives of 2-azidoadenine and 6-azidopurines have been synthesized. The azido-tetrazolo tautomerism observed on such nucleoside analogues has been studied. The compounds were tested for their activity against HIV and HBV but they did not show significant antiviral effect.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adenine / analogs & derivatives*
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Adenine / chemical synthesis
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Adenine / chemistry
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Anti-HIV Agents / chemical synthesis
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Anti-HIV Agents / chemistry
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Anti-HIV Agents / pharmacology
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Antiviral Agents / chemical synthesis
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Antiviral Agents / chemistry
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Antiviral Agents / pharmacology
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Azides* / chemical synthesis
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HIV / drug effects
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Hepatitis B virus / drug effects
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Indicators and Reagents
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Models, Molecular
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Molecular Conformation
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Purines* / chemical synthesis
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Purines* / chemistry
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Stereoisomerism
Substances
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Anti-HIV Agents
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Antiviral Agents
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Azides
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Indicators and Reagents
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Purines
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Adenine