[Isolation and identification of the infective agent of severe acute respiratory syndrome (SARS) from a patient with atypical pneumonia]

Zh Mikrobiol Epidemiol Immunobiol. 2003 Sep-Oct:(5):109-12.
[Article in Russian]

Abstract

The virological, morphological, molecular biological and immunochemical study of the infective agent isolated from the patient with the symptoms of atypical pneumonia, hospitalized in the infectious department of the clinical hospital in Blagoveshchensk, was carried out. Thus the fact of the appearance of SARS virus on the territory of Russia was proved. The isolated infective agent, identified as coronavirus strain CoD, was partly characterized and deposited to the virus collection of the Center of Special Laboratory Diagnostics and Treatment of Quarantine and Exotic Infectious Diseases.

MeSH terms

  • Animals
  • Chlorocebus aethiops
  • Cytopathogenic Effect, Viral
  • Humans
  • Male
  • Pneumonia, Viral*
  • RNA, Viral / analysis
  • RNA, Viral / blood
  • Reverse Transcriptase Polymerase Chain Reaction
  • Severe Acute Respiratory Syndrome / diagnosis
  • Severe Acute Respiratory Syndrome / pathology
  • Severe Acute Respiratory Syndrome / virology*
  • Severe acute respiratory syndrome-related coronavirus / genetics
  • Severe acute respiratory syndrome-related coronavirus / immunology
  • Severe acute respiratory syndrome-related coronavirus / isolation & purification*
  • Severe acute respiratory syndrome-related coronavirus / ultrastructure
  • Vero Cells

Substances

  • RNA, Viral