[Clinical feature and surgical treatment of recurrent craniopharyngiomas]

Di Yi Jun Yi Da Xue Xue Bao. 2003 Oct;23(10):1078-81.
[Article in Chinese]

Abstract

Objective: To explore the clinical feature and surgical treatment of recurrent craniopharyngiomas.

Methods: The imaging features, intraoperative course, and postoperative outcomes of 83 patients with craniopharyngiomas were retrospectively analyzed.

Results: Of the 81 patients that survived, 19 experienced recurrence of the craniopharyngioma 6 to 62 months after the completion of the initial treatment, with recurrence rates of patients with total, subtotal and partial removal being 5.3%, 52.9%, and 100% respectively. Five of the 24 patients aged 6 years or older, who had an incomplete surgical removal, received radiation therapy, and only 1 of them experienced tumor recurrence (20%) whereas as many as 15 of the 19 patients (78.9%) did who did not received it.

Conclusion: Surgery resection should be the primary therapeutic option for patients with recurrent craniopharyngioma and radiation therapy should also be considered but only as adjuvant therapy.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Child, Preschool
  • Craniopharyngioma / pathology
  • Craniopharyngioma / physiopathology
  • Craniopharyngioma / surgery*
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / surgery*
  • Pituitary Neoplasms / pathology
  • Pituitary Neoplasms / physiopathology
  • Pituitary Neoplasms / surgery*
  • Retrospective Studies