Cyclodextrins and emulsions

Int J Pharm. 2003 Nov 6;266(1-2):85-90. doi: 10.1016/s0378-5173(03)00384-3.

Abstract

This paper synthesises the literature on interactions between cyclodextrins (CD) and fatty acids and glycerides, and explains how these interactions allow the use of cyclodextrins to stabilise emulsions. An example of formulation with cyclodextrins is given which discusses the preparation of simple o/w emulsions, the addition of a model active ingredient, and the preparation of multiple emulsions in the absence of preformed surface active agents.

Publication types

  • Review

MeSH terms

  • Animals
  • Chemistry, Pharmaceutical
  • Cyclodextrins / chemistry
  • Cyclodextrins / metabolism*
  • Emulsions / chemistry
  • Emulsions / metabolism*
  • Fatty Acids / chemistry
  • Fatty Acids / metabolism
  • Humans

Substances

  • Cyclodextrins
  • Emulsions
  • Fatty Acids