Sequence analysis of the ROB-1 beta-lactamase gene from Actinobacillus pleuropneumoniae

Vet Microbiol. 1992 Oct;32(3-4):319-25. doi: 10.1016/0378-1135(92)90154-l.

Abstract

The ROB-1 beta-lactamase gene from Actinobacillus pleuropneumoniae was cloned and sequenced. The structural gene encodes a 305 amino acid polypeptide. The ROB-1 beta-lactamase gene sequence is identical to that derived from Pasteurella haemolytica and only one amino acid different from that of Haemophilus influenzae, suggesting that they are derived from the same ancestor, and transformed from one to another.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Actinobacillus pleuropneumoniae / enzymology*
  • Actinobacillus pleuropneumoniae / genetics
  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Cloning, Molecular
  • DNA, Bacterial / chemistry*
  • Genes, Bacterial
  • Molecular Sequence Data
  • Plasmids
  • Sequence Analysis, DNA
  • Swine
  • beta-Lactamases / chemistry
  • beta-Lactamases / genetics*

Substances

  • DNA, Bacterial
  • beta-lactamse ROB-1
  • beta-Lactamases

Associated data

  • GENBANK/M65980