[Clinical evaluation of provitamin B5 drops and gel for postoperative treatment of corneal and conjuctival injuries]

Klin Oczna. 2003;105(3-4):175-8.
[Article in Polish]

Abstract

Purpose: Vitamins B group are important ingredients of coenzymes. Provitamin B5 dexpanthenol is necessary in the processes of reconstruction of epithelium, has regenerative and anti-inflammatory properties. Objective of the study was to determine how the wounds of cornea and/or conjunctiva heal upon the application of D-panthenol/the medicine has been developed in the Faculty of Pharmacy of the Medical University of Gdańsk/.

Material and methods: The activity of the medicine was tested in 40 eyes in the test group, a 40 eyes in the control group did not receive D-panthenol. The degree of the objective and subjective symptoms was assessed.

Results: The differences between the two groups commenced on the second day following the operation. Better effects were observed in patients receiving D-panthenol. Congestion and oedema of conjunctiva withdrew, the edges of wounds demonstrated smoothness and better adherence. Subjective feelings improved.

Conclusions: 1. Provitamin B5 contained in 5% drops and 5% gel of D-panthenol effectively accelerates the processes of healing the wounds of conjunctiva and cornea.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial
  • English Abstract

MeSH terms

  • Conjunctiva / injuries
  • Conjunctiva / surgery*
  • Cornea / surgery*
  • Corneal Injuries
  • Epithelium, Corneal
  • Eye Injuries / drug therapy
  • Eye Injuries / etiology
  • Gels
  • Humans
  • Keratotomy, Radial / adverse effects
  • Middle Aged
  • Ophthalmic Solutions
  • Pantothenic Acid / administration & dosage*
  • Pantothenic Acid / analogs & derivatives*
  • Phacoemulsification / adverse effects
  • Postoperative Care / methods*
  • Wound Healing / drug effects*

Substances

  • Gels
  • Ophthalmic Solutions
  • Pantothenic Acid
  • dexpanthenol