Extensive palliative surgery for advanced mesothelioma of the tunica vaginalis

Urology. 2003 Oct;62(4):748. doi: 10.1016/s0090-4295(03)00673-3.

Abstract

Malignant mesothelioma of the tunica vaginalis is a rare tumor managed principally by radical surgical resection. Chemotherapy and radiotherapy have limited efficacy. We report on a 67-year-old man with severe debilitation from multiple scrotal and inguinal recurrences of a malignant mesothelioma originating in the right tunica vaginalis. Local pain from extensive tumor spread prevented ambulation. Aggressive surgical debridement (total penectomy and scrotectomy) and perineal urethrostomy afforded the patient significant improvement in his quality of life before he finally died of the disease 3 years after diagnosis.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Cisplatin / administration & dosage
  • Combined Modality Therapy
  • Debridement
  • Deoxycytidine / administration & dosage
  • Deoxycytidine / analogs & derivatives*
  • Fatal Outcome
  • Gemcitabine
  • Humans
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / secondary
  • Male
  • Mesothelioma / drug therapy
  • Mesothelioma / radiotherapy
  • Mesothelioma / secondary
  • Mesothelioma / surgery*
  • Neoplasm Recurrence, Local / drug therapy
  • Neoplasm Recurrence, Local / radiotherapy
  • Neoplasm Recurrence, Local / surgery
  • Palliative Care*
  • Penis / surgery
  • Scrotum / surgery
  • Testicular Neoplasms / pathology
  • Testicular Neoplasms / surgery*
  • Urethra / surgery

Substances

  • Deoxycytidine
  • Cisplatin
  • Gemcitabine