Photochemical degradation performance of quinoline aqueous solution in the presence of H2O2 was carried out, and some intermediates produced during quinoline degradation were also identified tentatively. The experimental results showed that the advanced oxidation of quinoline by UV/H2O2 process accorded well with the pseudo first order kinetics, and the dependence of concentrations of H2O2 and quinoline, and pH value on the photodegradation kinetics has been investigated in detail. It is found that the concentrations of hydrogen peroxide and quinoline have opposite effect on photodegradation kinetics. That means the photodegradation rate of quinoline increased significantly as the hydrogen peroxide concentration increasing, while the photodegradation rate decreased critically as the initial concentration of quinoline increasing. It also concluded that the photodegradation of quinoline by H2O2/UV process is more favorable under alkali solution than acid solution.