Use of hepatitis B virus DNA quantitation to predict hepatitis B e antigen reversion in cases of chronic hepatitis B

J Clin Microbiol. 2003 Oct;41(10):4793-5. doi: 10.1128/JCM.41.10.4793-4795.2003.

Abstract

Seventy-three chronic hepatitis B patients who had either hepatitis B e antigen (HBeAg) seroconversion (group I) or HBeAg-negative disease (group II) were studied. HBV DNA levels at HBeAg seroconversion (group I) and at initial visits (group II) were significantly lower among patients who were persistently negative for HBeAg than among those who underwent HBeAg reversion.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • DNA, Viral / blood*
  • Female
  • Hepatitis B Antibodies / blood*
  • Hepatitis B e Antigens / analysis*
  • Hepatitis B e Antigens / immunology
  • Hepatitis B virus / immunology
  • Hepatitis B virus / isolation & purification
  • Hepatitis B, Chronic / virology*
  • Humans
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Remission Induction
  • Viral Load*

Substances

  • DNA, Viral
  • Hepatitis B Antibodies
  • Hepatitis B e Antigens