[Successful treatment of bronchiolitis obliterans organizing pneumonia with cyclosporin and steroids]

Nihon Kokyuki Gakkai Zasshi. 2003 Aug;41(8):551-5.
[Article in Japanese]

Abstract

A 71-year-old woman with fever and dry cough was admitted to our hospital. Chest computed tomography, bronchoalveolar lavage and transbronchial lung biopsy were performed, and bronchiolitis obliterans organizing pneumonia (BOOP) was diagnosed. The patient was treated with corticosteroid, and marked improvement was noted. However, when the dosage was tapered, the BOOP recurred. We increased the dosage of corticosteroid and also put the patient on a daily regimen of cyclosporin. The cyclosporin was administered orally, and was effective, so that we could gradually decrease the dosage of corticosteroid. We concluded that cyclosporin may be useful in the treatment of refractory BOOP.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Inflammatory Agents / administration & dosage*
  • Cryptogenic Organizing Pneumonia / diagnosis
  • Cryptogenic Organizing Pneumonia / drug therapy*
  • Cryptogenic Organizing Pneumonia / pathology
  • Cyclosporine / administration & dosage*
  • Drug Therapy, Combination
  • Female
  • Humans
  • Immunosuppressive Agents / administration & dosage*
  • Lung / diagnostic imaging
  • Lung / pathology
  • Prednisolone / administration & dosage*
  • Recurrence
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Anti-Inflammatory Agents
  • Immunosuppressive Agents
  • Cyclosporine
  • Prednisolone