It has been recently recognized that angiotensin II (Ang II), in addition to its role in the regulation of the salt-fluid homeostasis is also a growth factor and contributes to the regulation of cellular hypertrophy or proliferation and extracellular matrix (ECM) formation. This article gives an overview on the role of mitogen activated protein kinase (MAPK) cascades in transducing the growth factor-like effects of Ang II.