Abstract
A series of N1-aryliden-2-pyridincarboxyamidrazone derivatives was prepared. Some of the synthesized compounds showed interesting in vitro antimycobacterial activity against some strains of Mycobacterium and clinical isolates of Mycobacterium tuberculosis.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / chemical synthesis*
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Anti-Bacterial Agents / pharmacology
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Antitubercular Agents / chemical synthesis
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Antitubercular Agents / pharmacology
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Drug Resistance, Microbial
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Microbial Sensitivity Tests
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Mycobacterium / drug effects*
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Mycobacterium tuberculosis / drug effects
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Pyridines / chemical synthesis*
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Pyridines / pharmacology
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Structure-Activity Relationship
Substances
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Anti-Bacterial Agents
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Antitubercular Agents
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Pyridines