The GnRH 10 micrograms test promotes a maximal gonadotropic response in normal women

Gynecol Endocrinol. 1992 Sep;6(3):167-70. doi: 10.3109/09513599209015551.

Abstract

The authors have compared the results of gonadotropin stimulation with a gonadotropin releasing hormone (GnRH) intravenous bolus of 100 micrograms and of 10 micrograms in a group of eumenorrheic women. They conclude that there are no differences between the responses of the two dosages in normal women. Therefore the authors clarify that the dosage of 10 micrograms of GnRH as a bolus test may be used currently in clinical practice in order to assess gonadotropic function.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Dose-Response Relationship, Drug
  • Female
  • Follicle Stimulating Hormone / blood*
  • Gonadotropin-Releasing Hormone / administration & dosage*
  • Humans
  • Luteinizing Hormone / blood*

Substances

  • Gonadotropin-Releasing Hormone
  • Luteinizing Hormone
  • Follicle Stimulating Hormone