Purification and partial characterization of anti-inflammatory peptide from pilose antler of Cervus nippon Temminck

Z Q Zhang; Y Zhang; B X Wang; H O Zhou; Y Wang; H Zhang

Purification and partial characterization of anti-inflammatory peptide from pilose antler of Cervus nippon Temminck

Yao Xue Xue Bao. 1992;27(5):321-4.

Authors

Z Q Zhang¹, Y Zhang, B X Wang, H O Zhou, Y Wang, H Zhang

Affiliation

¹ Department of Pharmacology, Academy of Traditional Chinese Medicine and Materia Medica of Jilin Province, Changchun.

PMID: 1442050

Abstract

An anti-inflammatory compound was purified and isolated from pilose antler of Cervus nippon Temminck by dialysis, gel filtration and ion-exchange chromatography techniques. HPLC and N-terminal amion acid analysis identified the compound as a homogeneous peptide. The peptide is composed of 68 amino acids and its molecular weight as determined by amino analysis, is about 7200.

MeSH terms

Amino Acids / analysis
Animals
Anti-Inflammatory Agents, Non-Steroidal / chemistry
Anti-Inflammatory Agents, Non-Steroidal / isolation & purification*
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
Antlers / chemistry*
Deer*
Edema / drug therapy
Materia Medica / chemistry*
Peptides / chemistry
Peptides / isolation & purification*
Peptides / therapeutic use
Rats

Substances

Amino Acids
Anti-Inflammatory Agents, Non-Steroidal
Materia Medica
Peptides