Investigation of the reparative histogenesis in patients with zygomatic bone fractures suffered in different periods in the past included histologic study of the tissue specimens taken from fracture sites during surgical intervention, studies of the osteogenesis, topographic-anatomic position of bone fragments, their mobility and configuration, and clinical and pathomorphologic changes in the soft tissues adjacent to the fracture site. Specific features of the reparative osteogenesis of the facial skull flat bones and changes in the soft tissues adjacent to the fracture site were detected.