Veralipride-induced tardive dystonia in a patient with bipolar psychosis

Ital J Neurol Sci. 1992 Oct;13(7):621-3. doi: 10.1007/BF02233409.

Abstract

Veralipride is a benzamide derivative effective in the treatment of menopausal syndrome. Despite its antidopaminergic action, extrapyramidal side effects seem to be very uncommon. We observed a patient with bipolar psychosis, who developed segmental dystonia after taking the drug. The disorder slowly receded in 14 months, but reappeared during neuroleptic therapy a few months later. To the best of our knowledge, this is the first case of veralipride-induced tardive dystonia, and the affective disorder might have predisposed our patient to the development of this tardive side effect.

Publication types

  • Case Reports

MeSH terms

  • Dystonia / chemically induced*
  • Female
  • Humans
  • Menopause
  • Middle Aged
  • Psychotic Disorders / complications
  • Sulpiride / adverse effects
  • Sulpiride / analogs & derivatives*
  • Sulpiride / therapeutic use

Substances

  • Sulpiride
  • veralipride