Tumors induced in primates by chicken sarcoma virus

Science. 1963 Jun 28;140(3574):1415-6. doi: 10.1126/science.140.3574.1415.

Abstract

A suspension of a variant of Rous sarcoma was injected into four adult and eight newborn rhesus monkeys. Seven newborns developed tumors, three of which were diagnosed as fibrosarcomas, in 2 to 6 weeks; none of the adults have tumors after 11 weeks. Virus was demonstrated in two of the tumors by injecting a tumor-suspension preparation into the chick wing-web where tumors subsequently appeared. To the best of our knowledge this is the first time that sarcomas have developed in primates after a virus has been injected.

MeSH terms

  • Animals
  • Avian Sarcoma Viruses*
  • Chickens*
  • Meat*
  • Neoplasms*
  • Primates*
  • Rous sarcoma virus*
  • Sarcoma, Avian*
  • Sarcoma, Experimental*