Localized non-Hodgkin's lymphoma of the adrenal and thyroid glands

Endocrinol Jpn. 1992 Jun;39(3):269-76. doi: 10.1507/endocrj1954.39.269.

Abstract

A case of immunoblastic lymphoma, involving only the thyroid and the adrenal glands, is presented. The patient had clinical symptoms and findings of Addison's disease, and computed tomography (CT) demonstrated bilateral adrenal tumoral enlargement. He also had euthyroid diffuse multinodular goiter. The diagnosis of the patient was based on the cytological examination of the aspiration materials from both endocrine glands. The patient received "m-BNCOD" chemotherapy regimen and replacement therapy for Addison's disease. At the end of three courses, a partial response was obtained.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Addison Disease / drug therapy
  • Addison Disease / etiology
  • Adrenal Gland Neoplasms / complications
  • Adrenal Gland Neoplasms / diagnosis*
  • Adrenal Gland Neoplasms / drug therapy
  • Adrenal Glands / diagnostic imaging
  • Adrenocorticotropic Hormone / blood
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Biopsy, Needle
  • Bleomycin / therapeutic use
  • Cyclophosphamide / therapeutic use
  • Dexamethasone / therapeutic use
  • Fludrocortisone / therapeutic use
  • Goiter, Nodular / etiology
  • Humans
  • Hydrocortisone / blood
  • Hydrocortisone / therapeutic use
  • Lymphoma, Non-Hodgkin / complications
  • Lymphoma, Non-Hodgkin / diagnosis*
  • Lymphoma, Non-Hodgkin / drug therapy
  • Male
  • Methotrexate / therapeutic use
  • Middle Aged
  • Mitoxantrone / therapeutic use
  • Thyroid Gland / diagnostic imaging
  • Thyroid Gland / pathology
  • Thyroid Neoplasms / complications
  • Thyroid Neoplasms / diagnosis*
  • Thyroid Neoplasms / drug therapy
  • Thyrotropin / blood
  • Thyroxine / blood
  • Tomography, X-Ray Computed
  • Triiodothyronine / blood
  • Ultrasonography
  • Vincristine / therapeutic use

Substances

  • Triiodothyronine
  • Bleomycin
  • Vincristine
  • Dexamethasone
  • Cyclophosphamide
  • Adrenocorticotropic Hormone
  • Thyrotropin
  • Mitoxantrone
  • Thyroxine
  • Fludrocortisone
  • Hydrocortisone
  • Methotrexate

Supplementary concepts

  • M-BNCOD protocol