Abstract
Eleven new derivatives of chelidonine I, obtained by functionalization of the alkaloid hydroxyl group, have been tested for CNS activity in mice exhibiting statistically significant effects.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkaloids / chemistry*
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Alkaloids / pharmacology*
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Animals
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Benzophenanthridines
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Berberine Alkaloids*
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Central Nervous System / drug effects*
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Central Nervous System / physiology
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Drug Evaluation, Preclinical / methods
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Male
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Mice
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Phenanthridines*
Substances
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Alkaloids
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Benzophenanthridines
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Berberine Alkaloids
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Phenanthridines
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chelidonine