Characterization of alternative routes for processing of the Alzheimer beta/A4-amyloid precursor protein. Differential effects of phorbol esters and chloroquine

Ann N Y Acad Sci. 1992 Dec 31:674:203-17. doi: 10.1111/j.1749-6632.1992.tb27489.x.

Authors

S E Gandy¹, G L Caporaso, T V Ramabhadran, T Suzuki, J D Buxbaum, C Nordstedt, K Iverfeldt, A J Czernik, A C Nairn, P Greengard

Affiliation

¹ Laboratory of Molecular and Cellular Neuroscience, Rockefeller University, New York, New York 10021.

PMID: 1363189
DOI: 10.1111/j.1749-6632.1992.tb27489.x

No abstract available

Publication types

Research Support, U.S. Gov't, P.H.S.
Review

MeSH terms

Alzheimer Disease / metabolism*
Amino Acid Sequence
Amyloid beta-Protein Precursor / metabolism*
Amyloidosis / genetics
Animals
Brain Diseases / genetics
Endopeptidases / metabolism
Humans
Molecular Sequence Data
Protein Processing, Post-Translational* / drug effects

Substances

Amyloid beta-Protein Precursor
Endopeptidases

Grants and funding