Entomological data generated in five entomological zones, of Madhya Pradesh State during 1991 including, Bhopal, Bilaspur, Gwalior, Indore and Raipur were analyzed. The entomological parameters that were studied included per man hour (pmh) density, abdominal physiology and parity status. The inferences were related to i) resting behaviour (exophily/endophily) ii) duration of indoor resting period of mosquitoes iii) man-vector contact iv) efficacy of residual insecticide and v) vulnerability of the area to focal malaria outbreaks. The data chiefly pertains to the putative malaria vector Anopheles culicifacies in all the five zones under study. The studies have brought out that A. culicifacies, traditionally endophilic and endophagic, has demonstrated radical departure in its resting and feeding behaviour. In Gwalior zone the species shows high preference for exophily. In Bhopal and Indore zones there is differential resting behaviour with respect to season. The species shows, for most part of the year exophily but is also endophilic during post monsoon period. In Bilaspur zone the species shows marked exophily and endophagy. Irrigation practices seem to have affected the mosquito population density patterns in these regions as brought out in Indore and Bilaspur zone, where high density pattern is observed between November and February. These findings have obvious implications in selecting the appropriate intervention methods and the period of spray in areas where residual spray is the method of choice for interruption of transmission.