Comparison between first and second generation tests to determine the frequency of anti-HCV antibodies in uremic patients in replacement dialytic therapy

Nephron. 1992;61(3):354-5. doi: 10.1159/000186940.

Abstract

Research was carried out on 74 hemodialysis patients to determine the frequency of anti-HCV antibodies; this was done by means of the 1st and 2nd generation screening and control tests. The 1st generation tests showed 9 HCV-seropositive patients, while the 2nd generation tests demonstrated 15 HCV-seropositive patients. It seems evident that the 2nd generation tests are more sensitive than those of the 1st.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Enzyme-Linked Immunosorbent Assay / methods
  • Enzyme-Linked Immunosorbent Assay / statistics & numerical data
  • Female
  • Hepacivirus / immunology*
  • Hepatitis Antibodies / blood*
  • Hepatitis C / diagnosis
  • Hepatitis C / immunology
  • Humans
  • Immunoassay / methods*
  • Immunoassay / statistics & numerical data
  • Immunoblotting / methods
  • Immunoblotting / statistics & numerical data
  • Male
  • Middle Aged
  • Renal Dialysis / adverse effects
  • Sensitivity and Specificity
  • Uremia / therapy

Substances

  • Hepatitis Antibodies