Abstract
Immunotherapy was attempted in 2 Arabian foals with combined immunodeficiency. One foal was given a transplant of bone marrow from a selected full sibling, and 1 foal was given a fetal thymus transplant. Both foals died. Genetic evidence was obtained for survival of the transplanted tissues in both cases; however, a graft versus host reaction developed in the foal given the fetal thymus transplant.
Publication types
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Case Reports
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Antigens
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Blood Group Antigens
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Bone Marrow Cells*
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Bone Marrow Transplantation*
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Erythrocytes / immunology
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Female
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Graft vs Host Reaction*
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Horse Diseases / immunology
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Horse Diseases / pathology
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Horse Diseases / therapy*
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Horses
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Immunologic Deficiency Syndromes / immunology
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Immunologic Deficiency Syndromes / therapy
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Immunologic Deficiency Syndromes / veterinary*
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Immunotherapy / veterinary*
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Kidney / pathology
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Leukocyte Count
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Lymphocyte Activation
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Skin / pathology
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Thymus Gland / transplantation*
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Transplantation, Homologous
Substances
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Antigens
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Blood Group Antigens