Ten Merino ewes were given a single Permasel pellet (containing 5% of elementary selenium) orally and examined for the release of selenium in the reticulum by determining glutathione enzyme activity of the whole blood haemolysate over a period of 12 months. As compared to the controls, the treated ewes exhibited a significant elevation in glutathione peroxidase activity for 8 months, indicating an acceptable persistence of the product tested.