Association of myocardial viability on nitrate-augmented technetium-99m hexakis-2-methoxylisobutyl isonitrile myocardial tomography and intermediate-term outcome in patients with prior myocardial infarction and left ventricular dysfunction

Am J Cardiol. 2003 Sep 15;92(6):696-9. doi: 10.1016/s0002-9149(03)00827-0.

Abstract

Seventy-eight patients with prior myocardial infarction and left ventricular dysfunction who underwent nitrate-augmented myocardial tomography were followed for 23 +/- 14 months. Event-free survival was 100% in 34 patients with myocardial viability who underwent coronary artery bypass grafting (CABG) and 53% in those who received medical therapy (p = 0.0008). Of the 44 patients without myocardial viability, event-free survival was not significantly different between patients who underwent CABG and those who received medical therapy (96% vs 90%, p = NS).

Publication types

  • Evaluation Study

MeSH terms

  • Aged
  • Disease-Free Survival
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction / diagnostic imaging*
  • Myocardial Infarction / physiopathology
  • Myocardial Infarction / therapy*
  • Nitrates*
  • Outcome Assessment, Health Care*
  • Predictive Value of Tests
  • Prognosis
  • Radiopharmaceuticals*
  • Retrospective Studies
  • Technetium Tc 99m Sestamibi*
  • Time Factors
  • Tissue Survival / physiology*
  • Tomography, Emission-Computed, Single-Photon*
  • Ventricular Dysfunction, Left / diagnostic imaging*
  • Ventricular Dysfunction, Left / physiopathology
  • Ventricular Dysfunction, Left / therapy*

Substances

  • Nitrates
  • Radiopharmaceuticals
  • Technetium Tc 99m Sestamibi