Group B Streptococcal (GBS) antibiotic susceptibility studies were performed in 95 pregnant women in Bridgeport, Connecticut. Testing for penicillin, ampicillin, cefazolin, and clindamycin sensitivity was performed. Resistance to clindamycin was seen in 5% of isolates. All isolates were susceptible to penicillin, ampicillin, and cefazolin. Clindamycin sensitivity testing should be performed in patients who are allergic to penicillin. GBS remained uniformly susceptible to penicillin and first generation cephalosporins during this study period.