Two new macrocyclic diaryl ether heptanoids from Boswellia ovalifoliolata

Vanimireddy Lakshmi Niranjan Reddy; Kodela Ravinder; Masuna Srinivasulu; Thirumani Venkateshwar Goud; Samala Malla Reddy; Dondapati Srujankumar; Tadikamalla Prabhakar Rao; Upadhyayula Suryanarayana Murty; Yenamandra Venkateswarlu

doi:10.1248/cpb.51.1081

Two new macrocyclic diaryl ether heptanoids from Boswellia ovalifoliolata

Chem Pharm Bull (Tokyo). 2003 Sep;51(9):1081-4. doi: 10.1248/cpb.51.1081.

Authors

Vanimireddy Lakshmi Niranjan Reddy¹, Kodela Ravinder, Masuna Srinivasulu, Thirumani Venkateshwar Goud, Samala Malla Reddy, Dondapati Srujankumar, Tadikamalla Prabhakar Rao, Upadhyayula Suryanarayana Murty, Yenamandra Venkateswarlu

Affiliation

¹ Natural Products Laboratory, Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad.

PMID: 12951452
DOI: 10.1248/cpb.51.1081

Abstract

The stems of Boswellia ovalifoliolata BAL. & HENRY (Burseraceae) afforded two new macrocyclic diaryl ether heptanoids, ovalifoliolatin A (1) and B (2) together with three known compounds; acerogenin C (3), 3 alpha-hydroxyurs-12-ene (4), and sitost-4-en-3-one (5). The structures were established by means of spectroscopic analysis and compounds 1, 3-5 were evaluated for their antibacterial activity.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / chemistry
Anti-Bacterial Agents / isolation & purification
Anti-Bacterial Agents / pharmacology
Bacteria / drug effects
Boswellia / chemistry*
Ethers, Cyclic / chemistry*
Ethers, Cyclic / isolation & purification
Ethers, Cyclic / pharmacology
Magnetic Resonance Spectroscopy
Microbial Sensitivity Tests
Models, Molecular
Molecular Conformation
Spectrometry, Mass, Fast Atom Bombardment
Structure-Activity Relationship

Substances

Anti-Bacterial Agents
Ethers, Cyclic
ovalifoliolatin A
ovalifoliolatin B