Abstract
Forty Japanese anti-SSA(Ro) positive patients with Sjögren's syndrome were typed for HLA-A, B, C, DR and DQ antigens. No patient had either HLA-B8 or HLA-DR3 which has been reportedly associated with the immune response to SSA(Ro) antigens in white and black patients. Our patients had higher frequencies of HLA-DRw8 and HLA-DRw52 than the control population.
MeSH terms
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Adolescent
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Adult
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Aged
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Autoantigens / analysis*
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Female
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HLA-B8 Antigen / analysis*
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HLA-DR3 Antigen / analysis*
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Humans
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Japan / epidemiology
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Male
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Middle Aged
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RNA, Small Cytoplasmic*
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Ribonucleoproteins / analysis*
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Sjogren's Syndrome / epidemiology
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Sjogren's Syndrome / immunology*
Substances
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Autoantigens
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HLA-B8 Antigen
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HLA-DR3 Antigen
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RNA, Small Cytoplasmic
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RO60 protein, human
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Ribonucleoproteins
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SS-A antigen