A new successful therapy for fetal chylothorax by intrapleural injection of maternal blood

Ultrasound Obstet Gynecol. 2003 Sep;22(3):290-4. doi: 10.1002/uog.208.

Abstract

We present two cases of fetal chylothorax and hydrops diagnosed at 20 weeks' gestation, both of which underwent successful intrauterine treatment. In Case 1, a transient, near total resolution began 2 weeks after an iatrogenic hemothorax following a second thoracocentesis performed at 24 + 6 weeks. Because of pleural fluid reaccumulation, a Cesarean section was performed at 36 weeks. The 3805-g female neonate was admitted to neonatal intensive care but was discharged 50 days later in a healthy condition. In Case 2, resolution occurred after a third thoracocentesis and a second pleural injection of maternal blood, performed at 26 weeks. A 2660-g female neonate was delivered vaginally at 38 weeks. The infant remained asymptomatic and was discharged aged 4 days. Our experience suggests a possible useful role of intrapleural blood injection for the treatment of fetal chylothorax.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Ascites / diagnostic imaging
  • Blood*
  • Chylothorax / diagnostic imaging
  • Chylothorax / therapy*
  • Female
  • Fetal Diseases / diagnostic imaging
  • Fetal Diseases / therapy*
  • Hemothorax / diagnostic imaging
  • Humans
  • Injections
  • Paracentesis
  • Pregnancy
  • Prenatal Care / methods
  • Ultrasonography