Antifungal and antibacterial activity of 2-acetylpyridine-(4-phenylthiosemicarbazone) and its metal (II) complexes

Farmaco. 1992 Dec;47(12):1543-54.

Abstract

2-Acetylpyridine-(4-phenylthiosemicarbazone) and its metal (II) complexes have been synthesized and characterized by chemical and spectral methods. They were studied for their antibacterial and antifungal activities in vitro. The ligand and its metal (II) complexes exibited significant activity against a wide spectrum of bacteria and fungi.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents
  • Anti-Infective Agents / chemical synthesis*
  • Anti-Infective Agents / pharmacology
  • Antifungal Agents / chemical synthesis*
  • Antifungal Agents / pharmacology
  • Bacteria / drug effects
  • Fungi / drug effects
  • Microbial Sensitivity Tests
  • Thiosemicarbazones / chemical synthesis*
  • Thiosemicarbazones / pharmacology

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antifungal Agents
  • Thiosemicarbazones
  • 2-acetylpyridine-(4-phenylthiosemicarbazone)