Abstract
The Lyme disease spirochete, Borrelia burgdorferi, utilizes a LuxS/autoinducer-2-dependent quorum sensing mechanism to control a specific subset of bacterial proteins. It is hypothesized that this system facilitates transmission of B. burgdorferi from feeding ticks into warm-blooded hosts.
Publication types
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Bacterial Proteins / genetics
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Bacterial Proteins / metabolism*
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Borrelia burgdorferi / genetics
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Borrelia burgdorferi / metabolism*
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Borrelia burgdorferi / physiology
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Carbon-Sulfur Lyases
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Humans
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Lyme Disease / microbiology
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Lyme Disease / transmission*
Substances
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Bacterial Proteins
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Carbon-Sulfur Lyases
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LuxS protein, Bacteria