The determination of trace lead in Huaiyao after separating and enriching with sulfhydryl cotton by FAAS is described in this paper. The enriching and eluting conditions were studied. The recovery of lead is 97.0%-102.0%. RSD is less than 4.3% sulfhydryl cotton is effective in eliminating the interference for common existing elements. The characteristics of this method is fast, simple and convenient. The determine results were consistent.