Disk diffusion-based methods for determining Candida parapsilosis susceptibility to anidulafungin

Antimicrob Agents Chemother. 2003 Sep;47(9):3018-20. doi: 10.1128/AAC.47.9.3018-3020.2003.

Abstract

Zone diameters for anidulafungin by disk diffusion for 139 isolates of C. parapsilosis were compared with MICs by NCCLS M27-A2 broth microdilution. The comparison was poor unless the disks were prepared by dissolving anidulafungin in 1% dimethyl sulfoxide plus 0.1% Tween 80 and testing on Mueller-Hinton agar flooded with glucose and methylene blue.

Publication types

  • Comparative Study

MeSH terms

  • Anidulafungin
  • Antifungal Agents / pharmacology*
  • Candida / drug effects*
  • Culture Media
  • Diffusion
  • Echinocandins
  • Microbial Sensitivity Tests
  • Peptides, Cyclic / pharmacology*
  • Solvents

Substances

  • Antifungal Agents
  • Culture Media
  • Echinocandins
  • Peptides, Cyclic
  • Solvents
  • Anidulafungin