Promoter hypermethylation in cancer silences LDHB, eliminating lactate dehydrogenase isoenzymes 1-4

Clin Chem. 2003 Sep;49(9):1518-20. doi: 10.1373/49.9.1518.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Colorectal Neoplasms / enzymology
  • Colorectal Neoplasms / metabolism
  • DNA Methylation*
  • Gene Silencing*
  • Humans
  • Isoenzymes / genetics
  • Isoenzymes / metabolism
  • L-Lactate Dehydrogenase / genetics*
  • L-Lactate Dehydrogenase / metabolism
  • Polymorphism, Single-Stranded Conformational
  • Promoter Regions, Genetic*
  • Protein Subunits / genetics
  • Stomach Neoplasms / enzymology
  • Stomach Neoplasms / metabolism
  • Tumor Cells, Cultured

Substances

  • Isoenzymes
  • Protein Subunits
  • L-Lactate Dehydrogenase
  • lactate dehydrogenase 2
  • lactate dehydrogenase 3
  • lactate dehydrogenase 4
  • lactate dehydrogenase 1