Quantification of functional group interactions in transition states

J Am Chem Soc. 2003 Aug 20;125(33):9936-7. doi: 10.1021/ja034767d.

Authors

Christopher A Hunter¹, Caroline M R Low, Jeremy G Vinter, Cristiano Zonta

Affiliation

¹ Centre for Chemical Biology, Krebs Institute for Biomolecular Science, Department of Chemistry, University of Sheffield, Sheffield S3 7HF, UK. c.hunter@shef.ac.uk

PMID: 12914452
DOI: 10.1021/ja034767d

Abstract

A new version of the double mutant cycle approach has been used for the evaluation of weak noncovalent interactions in transition states.