Abstract
The synthesis of 2-substituted isomers of the meridianins, a familiy of bioactive indole alkaloids isolated from the tunicate Aplidium meridianum, was undertaken. The synthetic route comprises six steps, with a microwave promoted Fischer cyclization as the key reaction.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Indole Alkaloids / chemical synthesis
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Indoles / chemical synthesis*
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Pyrimidines / chemical synthesis*
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Urochordata
Substances
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Indole Alkaloids
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Indoles
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Pyrimidines
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pyrimidine