Abstract
The Agrobacterium tumefaciens C58 genome contains three putative N-acyl homoserine lactone (acyl-HSL) hydrolases, which are closely related to the lactonase AiiA of Bacillus. When expressed in Escherichia coli, two of the putative acyl-HSL hydrolases, AttM and AiiB, conferred the ability to degrade acyl-HSLs on the host. In Erwinia strain 6276, the lactonases reduced the endogenous acyl-HSL level and the bacterial virulence in planta.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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4-Butyrolactone / analogs & derivatives*
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4-Butyrolactone / metabolism
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Agrobacterium tumefaciens / enzymology
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Agrobacterium tumefaciens / genetics*
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Amino Acid Sequence
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Carboxylic Ester Hydrolases / genetics*
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Hydrolases / genetics
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Molecular Sequence Data
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Plant Tumor-Inducing Plasmids*
Substances
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homoserine lactone
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Hydrolases
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Carboxylic Ester Hydrolases
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N-acyl homoserine lactonase
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4-Butyrolactone