Germacranolides from seeds of the endangered Umbelliferae species Rouya polygama

Bernard Muckensturm; Fatih Sen; Anna Boulanger; Jean Pierre Reduron

doi:10.1016/s0031-9422(03)00223-1

Germacranolides from seeds of the endangered Umbelliferae species Rouya polygama

Phytochemistry. 2003 Aug;63(8):863-7. doi: 10.1016/s0031-9422(03)00223-1.

Authors

Bernard Muckensturm¹, Fatih Sen, Anna Boulanger, Jean Pierre Reduron

Affiliation

¹ Université de Haute Alsace, Ecole Nationale Supérieure de Chimie de Mulhouse, 3 rue Alfred Werner, F-68093 Cedex, Mulhouse, France. b.muckenstrum@uha.fr

PMID: 12895531
DOI: 10.1016/s0031-9422(03)00223-1

Abstract

From the etheral extract of Rouya polygama Coincy seeds (Umbelliferae) six new germacranolides 1-6 were isolated. The structures were elucidated by chemical methods and spectroscopic analysis. Compounds 1 and 4 exhibited activity against Artemia salina larvae.

MeSH terms

Animals
Apiaceae / chemistry*
Artemia / drug effects
Larva / drug effects
Magnetic Resonance Spectroscopy
Molecular Structure
Seeds / chemistry
Sesquiterpenes / chemistry*
Sesquiterpenes / isolation & purification
Sesquiterpenes / pharmacology

Substances

Sesquiterpenes