A finite element model for ice ball evolution in a multi-probe cryosurgery

Comput Methods Biomech Biomed Engin. 2003 Jun;6(3):197-208. doi: 10.1080/1025584031000151185.

Abstract

The ice formation in a water body is examined for the computation of temperature field, phase change and a moving ice-water interface whose location is not known á priori. This is classically referred to as the Stefan problem [Rubinstein, L.I. (1971) The Stefan Problem (American Mathematical Society, Providence, Rhode Island 02904]. Based on the Duvaut [Duvaut, G. (1973) "Résolution d'un probléme Stefan" C.R. Acad Sci. Paris 276, 1461-1463] transformation, the governing equations for heat conduction are formulated within a variational principle that is readily amenable to a standard finite element solution without remeshing. Numerical simulation results pertaining to the freezing of tumour tissue in a multi-cryoprobe cryosurgery are presented. These results lend both quantitative and graphical support to the current empirical standards of "effective therapy" in view of refining clinical applications.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Animals
  • Body Temperature
  • Computer Simulation
  • Cryosurgery / methods*
  • Crystallization / methods
  • Finite Element Analysis
  • Freezing*
  • Humans
  • Ice*
  • Models, Biological*
  • Neoplasms / physiopathology*
  • Neoplasms / surgery*
  • Thermal Conductivity
  • Thermography / methods*

Substances

  • Ice