Abstract
Haematococcus pluvialis was mutated by UV or ethyl methanesulphonate. Mutants resistant to nicotine, diphenylamine, fluridone or norflurazon were then selected. Several nicotine-resistant mutants showed increased (1.9% to 2.5% vs. 1.2% w/w) astaxanthin production. Mutants maintained high astaxanthin production over 4 months of repeated culture.
MeSH terms
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Biotechnology / methods*
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Chlorophyta / drug effects
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Chlorophyta / physiology*
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Chlorophyta / radiation effects
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Diphenylamine / pharmacology
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Ethyl Methanesulfonate / pharmacology
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Mutagenesis
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Mutation*
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Nicotine / pharmacology
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Pyridazines / pharmacology
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Pyridones / pharmacology
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Ultraviolet Rays
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Xanthophylls
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beta Carotene / analogs & derivatives*
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beta Carotene / biosynthesis*
Substances
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Pyridazines
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Pyridones
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Xanthophylls
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beta Carotene
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fluridone
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Nicotine
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astaxanthine
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Ethyl Methanesulfonate
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Diphenylamine
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norflurazone