Anti-atherogenic effects of 3,4-Dihydroxy hydrocinnamides

Bioorg Med Chem Lett. 2003 Aug 18;13(16):2681-2. doi: 10.1016/s0960-894x(03)00549-3.

Abstract

3,4-Dihydroxy hydrocinnamides 2 and 3 exhibited the anti-atherogenic activities by inhibiting the formation of aortic fatty streak in high cholesterol-fed rabbits.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amides / chemical synthesis*
  • Amides / pharmacology
  • Animals
  • Aorta / drug effects
  • Aorta / metabolism
  • Aorta / pathology
  • Arteriosclerosis / blood
  • Arteriosclerosis / drug therapy
  • Cholesterol, Dietary / administration & dosage
  • Hypolipidemic Agents / chemical synthesis*
  • Hypolipidemic Agents / pharmacology
  • Lipid Metabolism
  • Lipids / blood
  • Phenylpropionates / chemical synthesis*
  • Phenylpropionates / pharmacology
  • Rabbits

Substances

  • Amides
  • Cholesterol, Dietary
  • Hypolipidemic Agents
  • Lipids
  • Phenylpropionates
  • 3-phenylpropionic acid