Measurements of optical properties of high-density media

Appl Opt. 2003 Jul 1;42(19):4023-30. doi: 10.1364/ao.42.004023.

Abstract

Measurements of optical properties (scattering coefficient mu(s), absorption coefficient mu(a), reduced scattering coefficient mu(s)', and asymmetry factor g) have been carried out up to a volume particle concentration of rho = 0.227. The results for mu(s) and mu(s)' show significant deviations from the linear dependence on rho as expected when the independent scattering assumption is fulfilled. The asymmetry factor also changed significantly. In contrast, the dependence of mu(a) remained linear even at the largest concentration investigated. The simple linear dependence of absorption on the chromophore concentration expected from the independent scattering assumption is thus applicable also to spectroscopic measurements of dense media. A comparison with an approximate theoretical model based on the Foldy-Twersky equation is also reported. The model provides a good description of the dependence of mu(s) on particle concentration.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Computer Simulation
  • Densitometry / instrumentation*
  • Densitometry / methods*
  • Fat Emulsions, Intravenous / chemistry*
  • Lasers*
  • Microspheres
  • Models, Theoretical
  • Optics and Photonics
  • Particle Size
  • Refractometry / instrumentation*
  • Refractometry / methods*
  • Reproducibility of Results
  • Scattering, Radiation*
  • Sensitivity and Specificity

Substances

  • Fat Emulsions, Intravenous