A new approach to the synthesis of the 5'-end substituted oligonucleotides using T4 polynucleotide kinase and gamma-amides of ATP bearing photoreactive groups

Dokl Biochem Biophys. 2003 Mar-Apr:389:114-7. doi: 10.1023/a:1023692324262.

Authors

I O Petrousseva¹, I V Safronov, N I Komarova, T P Kamynina, O I Lavrik, S N Khodyreva

Affiliation

¹ Novosibirsk Institute of Bioorganic Chemistry, Siberian Division, Russian Academy of Sciences, pr. Lavrent'eva 8, Novosibirsk, 630090 Russia.

PMID: 12856418
DOI: 10.1023/a:1023692324262

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adenosine Triphosphate / metabolism*
Amides / metabolism*
Animals
Bacteriophage T4 / enzymology
Light
Models, Molecular
Oligonucleotides / biosynthesis*
Oligonucleotides / chemistry*
Phosphorylation
Photoaffinity Labels
Photochemistry
Polynucleotide 5'-Hydroxyl-Kinase / metabolism*

Substances

Amides
Oligonucleotides
Photoaffinity Labels
Adenosine Triphosphate
Polynucleotide 5'-Hydroxyl-Kinase